What We Have Learned About Vitamin D Dosing – Thank You Dr. Dan Murphy!

What We Have Learned About Vitamin D Dosing?

Integrative Medicine
Vol. 9, No. 1, Feb/Mar 2010
Joseph Pizzorno, ND, Editor in Chief
The world standard uses nmol/l, while US standard uses mg/dl.
For vitamin D, to convert mg/dl to nmol/l, divide the mg/dl by 2.5.
For vitamin D, to convert nmol/l to mg/dl, just multiply by 2.5.
1) “Over the past several years, the surprising prevalence of vitamin D
deficiency has become broadly recognized.”
2) Vitamin D deficiency is linked to:
Cardiovascular disease
Autoimmune diseases
Multiple sclerosis
Loss of Cognitive function
Decreased strength
Increased rate of all-cause mortality
3) “Deficiency of vitamin D is now recognized as a pandemic, with more than
half of the world’s population at risk.”
4) Approximately 50% of the healthy North American population and more than
80% of those with chronic diseases are vitamin D deficient.
5) 80% of healthy Caucasian infants are vitamin D deficient. [And the rate of
vitamin D deficiency tends to be greater in African American and Hispanic children].
6) Those with vitamin D deficiency experience 39% higher annual healthcare
costs than those with normal levels of vitamin D.
7) Suggested levels of vitamin D as measured by 25(OH)D3 is:
Caucasians 125 – 175 nmol/l = 50 – 70 mg/dl
Hispanics 100 – 150 nmol/l = 40 – 60 mg/dl
African Americans 80 – 120 nmol/l = 32- 48 mg/dl
8) The minimum blood levels of vitamin D [25(OH)D3] is 80 nmol/l (32 mg/dl).
9) Prolonged intake of 10,000 IU of supplemental vitamin D3 “is likely to pose no
risk of adverse effects in almost all individuals.”
10) The maximum safe levels for vitamin 25(OH)D3 in the blood is 275 nmol/l
(100 mg/dl).
11) Sarcoidosis patients (and other granulomatous diseases) should not
supplement with vitamin D because it increases granuloma production increasing
the risk of hypercalcemia.
12) A loading dose of supplemental vitamin D3 of 10,000 IU/day for 3 months
and maintenance dose of 5,000 IU/day “is not enough for most people in northern
13) The loading dose of supplemental vitamin D3 should be about 20,000 IU/day
for 3 – 6 months with a maintenance dose of 5,000 IU/day. Those taking this
amount of supplemental vitamin D3 should periodically have their serum 25(OH)D3
levels measured.
The lab we use to test blood vitamin D3 [25(OH)D3] uses a finger prick analysis:
ZRT Laboratory
8605 SW Creekside Pl
Beaverton, OR 97008
Vitamin D Testing Finger prick
The vitamin D3 my family takes is Complete Hi D3, from Nutri-West (5,000 IU):
The primary researcher on this product was Don Bellgrau, PhD. Dr. Bellgrau is a
tenured Professor of Immunology and Medicine at the University of Colorado,
Denver, where he is a Program Leader in Immunology and Immunotherapy at the
Cancer Center on vitamin D3 supplementation. Dr. Bellgrau has conducted
experiments with nutrients/vitamin D and immune cells. He has published in over
100 peer-reviewed articles, including the Journal of Neurooncology, Nature, Clinical
Immunology, Cancer Research, Cancer Immunology and Immunotherapy, and Cell

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